Comparison of Pulmonary Artery Pressure before and after Kidney Transplantation in Kidney Transplant Patients with Pulmonary Hypertension

Autor: Sahar Ravanshad, Anoush Azarfar, Negin Jafarnezhad Sani, Maryam Miri, Yalda Ravanshad
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: ARYA Atherosclerosis, Vol 18, Iss November, Pp 1-6 (2022)
Druh dokumentu: article
ISSN: 1735-3955
2251-6638
DOI: 10.48305/arya.2022.11802.2458
Popis: Background: Pulmonary hypertension (PH) is a common finding in chronic kidney disease (CKD) and is associated with increased mortality and morbidity. The effect of kidney transplantation on PH is not yet well evaluated. This study aimed to compare pulmonary artery pressure (PAP) before and after kidney transplantation in CKD patients.Methods: This longitudinal study was conducted on 33 CKD patients who were candidates for kidney transplantation in a tertiary hospital in Mashhad, Iran. Pulmonary artery pressure and ejection fraction (EF) were assessed using trans-thoracic echocardiography (TTE). Demographic and clinical findings, including age, gender, and body mass index (BMI), as well as laboratory assessments, including hemoglobin, serum calcium and phosphorus level, and parathyroid hormone, were recorded before transplantation. TTE assessment was repeated one year after transplantation. Results: Mean age of the study patients (17 males and 16 females) was 30.42 ± 9.71 years. The majority of patients (85%) received hemodialysis before transplantation. Compared to before transplantation, PAP significantly decreased (from 33.67 ± 6.78 to 26.06 ± 5.78 mmHg, p
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