Desmoid-type fibromatosis in the setting of malignant peritoneal mesothelioma: a case report of two rare diseases

Autor: Stephanie N. Gregory, Audra A. Satterwhite, H. Richard Alexander, Andrew M. Blakely
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-4 (2022)
Druh dokumentu: article
ISSN: 1477-7819
DOI: 10.1186/s12957-022-02784-y
Popis: Abstract Background Desmoid-type fibromatosis (DTF) is a rare benign lesion that usually arises from the abdominal wall or extremities and rarely from the mesentery or intrabdominal organs. Malignant peritoneal mesothelioma is also a rare, yet aggressive disease. To our knowledge, this is the first case report of desmoid-type fibromatosis in the setting of malignant peritoneal mesothelioma. Case presentation An early 30-year-old female was referred to our center for large intra-abdominal mass concerning for recurrent malignant peritoneal mesothelioma after previous cytoreductive surgery with hyperthermic intraperitoneal chemotherapy and adjuvant chemotherapy. Further investigation revealed a large mesenteric mass, which was resected en bloc with the cecum and terminal ileum. Pathologic findings confirmed a surprising diagnosis of desmoid-type fibromatosis. Conclusions No adjuvant therapy was offered to this patient due to negative tumor margins; however, close follow-up will be provided for recurrence of both malignant peritoneal mesothelioma and desmoid-type fibromatosis, which can be differentiated in the future via biopsy in this patient.
Databáze: Directory of Open Access Journals
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