Systematic exploration of eczema‐associated paediatric diseases in a Chinese population of millions: A retrospective observation study

Autor: Huiwen Zheng, Jian Yang, Yuqing Feng, Huilong Duan, Lizhong Du, Qiang Shu, Haomin Li
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Clinical and Translational Allergy, Vol 13, Iss 5, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2045-7022
DOI: 10.1002/clt2.12249
Popis: Abstract Background Eczema is the most common form of dermatitis and also the starting point of atopic march. Although many eczema‐associated allergic and immunologic disorders have been studied, there remains a gap in the systematic quantitative knowledge regarding the relationships between all childhood disorders and eczema. This study aimed to systematically explore eczema‐associated childhood diseases using a real‐world, long‐term clinical dataset generated from millions of children in China. Methods Data were collected at 8,907,735 outpatient healthcare visits from 2,592,147 children between January 1, 2013, and August 15, 2019, at the largest comprehensive pediatric medical center in Zhejiang Province of China. The period prevalence differences in various pediatric diseases between children with and without eczema were used to test the independence of various pediatric disorders and eczema using Fisher's exact test. Bonferroni correction was used to adjust the p value in multiple testing. Odds ratio >2 with 95% confidence interval not including 1 and adjusted p
Databáze: Directory of Open Access Journals
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