ADP-induced platelet reactivity and bleeding events in patients with acute myocardial infarction complicated by cardiogenic shock

Autor: Clemens Scherer, Enzo Lüsebrink, Danny Kupka, Thomas J. Stocker, Konstantin Stark, Jan Kleeberger, Mathias Orban, Antonia Kellnar, Tobias Petzold, Simon Deseive, Kathrin Krieg, Sara Würbel, Sara Kika, Mario Istrefi, Stefan Brunner, Daniel Braun, Christian Hagl, Jörg Hausleiter, Steffen Massberg, Dirk Sibbing, Martin Orban
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Platelets, Vol 33, Iss 3, Pp 371-380 (2022)
Druh dokumentu: article
ISSN: 0953-7104
1369-1635
09537104
DOI: 10.1080/09537104.2021.1913577
Popis: While previous reports showed ADP-induced platelet reactivity to be an independent predictor of bleeding after PCI in stable patients, this has never been investigated in patients with cardiogenic shock. The association of bleeding events with respect to ADP-induced platelet aggregation was investigated in patients undergoing primary PCI for acute myocardial infarction complicated by cardiogenic shock and with available on-treatment ADP-induced platelet aggregation measurements. Out of 233 patients, 74 suffered from a severe BARC3 or higher bleed. ADP-induced platelet aggregation was significantly lower in patients with BARC≥3 bleedings (p
Databáze: Directory of Open Access Journals
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