Prospectives of T-cells genetic programming in adoptive immunotherapy of malignancies

Autor: O. L. Morozova, V. V. Yakovlev, N. A. Sushentsev
Jazyk: ruština
Rok vydání: 2022
Předmět:
Zdroj: Сеченовский вестник, Vol 0, Iss 3, Pp 23-28 (2022)
Druh dokumentu: article
ISSN: 2218-7332
2658-3348
Popis: The article reviews the literature on adoptive T-cell therapy of malignancies. Adoptive T-cell transfer allows treatment of metastatic disease on the late stages of certain tumors. The method has a number of advantages before traditional antitumor therapy. The special attention is paid to the possibility of adoptive cells genetic programming, which increases the treatment effectiveness and safety in cancer patients. The article also discusses the method introduction into clinical practice.
Databáze: Directory of Open Access Journals