Evaluation of the initial 12 months of a routine cryptococcal antigen screening program in reduction of HIV-associated cryptococcal meningitis in Uganda

Autor: Kagimu Enock, Kiwanuka Julius, Bridget C. Griffith, Derrick Bary Abila, Morris K. Rutakingirwa, John Kasibante, Kiiza Tadeo Kandole, Richard Kwizera, Aggrey Semeere, David B. Meya
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Health Services Research, Vol 22, Iss 1, Pp 1-8 (2022)
Druh dokumentu: article
ISSN: 1472-6963
15867579
DOI: 10.1186/s12913-022-07624-z
Popis: Abstract Background Asymptomatic Cryptococcal Antigenemia (CrAg) patients develop meningitis within a month of testing positive. Pre-emptive antifungal therapy can prevent progression to Cryptococcal meningitis (CM). In April 2016, a national CrAg screening program was initiated in 206 high-volume health facilities that provide antiretroviral therapy in Uganda. We report the evaluation of the CrAg screening cascade focusing on linkage to care, fluconazole therapy for 10 weeks and 6 months follow up, and ART initiation in a subset of facilities. Methods We conducted a retrospective, cross-sectional survey of patients with CD4
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje