Molecular characterization of pathogenic group B streptococcus from a tertiary hospital in Shanxi, China: High incidence of sequence type 10 strains in infants/pregnant women

Autor: Li Zhang, Lan Ma, Lei Zhu, Xiang-Hong Zhou, Li-Jun Xu, Chao Guo, Jin-Hua Meng, Xin-Hua Zhang, Qing-Hua Liu, Rui Huang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Microbiology, Immunology and Infection, Vol 54, Iss 6, Pp 1094-1100 (2021)
Druh dokumentu: article
ISSN: 1684-1182
DOI: 10.1016/j.jmii.2020.07.018
Popis: Background: Group B streptococcus (GBS) is a leading cause of serious infection in infants. Understanding its regional molecular epidemiology is helpful for regulating efficient prevention practice. Methods: A retrospective study was conducted to collected data from infants and pregnant women with culture-proven GBS disease in the largest women and children's medical center in Shanxi between January 2017 and September 2019. All GBS isolates were analyzed by multi-locus sequence typing (MLST) as well as distribution of pilus island (PI) genes. Results: A total of 54 GBS isolates were obtained from 36 (66.7%) pregnant women and 18 (33.3%) infants with invasive disease. Among invasive GBS strains, the most common sequence type was ST10 (72.2%, P
Databáze: Directory of Open Access Journals