Reliability of diurnal salivary cortisol metrics: A meta-analysis and investigation in two independent samples

Autor: Sara A. Norton, David AA. Baranger, Ethan S. Young, Michaela Voss, Isabella Hansen, Erin Bondy, Merlyn Rodrigues, Sarah E. Paul, Elizabeth Edershile, Patrick L. Hill, Thomas F. Oltmanns, Jeffry Simpson, Ryan Bogdan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Comprehensive Psychoneuroendocrinology, Vol 16, Iss , Pp 100191- (2023)
Druh dokumentu: article
ISSN: 2666-4976
DOI: 10.1016/j.cpnec.2023.100191
Popis: Stress-induced dysregulation of diurnal cortisol is a cornerstone of stress-disease theories; however, observed associations between cortisol, stress, and health have been inconsistent. The reliability of diurnal cortisol features may contribute to these equivocal findings. Our meta-analysis (5 diurnal features from 11 studies; total participant n = 3307) and investigation (15 diurnal cortisol features) in 2 independent studies (St. Louis Personality and Aging Network [SPAN] Study, n = 147, ages 61–73; Minnesota Longitudinal Study of Risk and Adaptation [MLSRA] Study, n = 90, age 37) revealed large variability in the day-to-day test-retest reliability of diurnal features derived from salivary cortisol data (i.e., ICC = 0.00–0.75). Collectively, these data indicate that some commonly used diurnal cortisol features have poor reliability that is insufficient for individual differences research (e.g., cortisol awakening response) while others (e.g., area under the curve with respect to ground) have fair-to-good reliability that could support reliable identification of associations in well-powered studies.
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