Evaluation of Antibacterial Activity of Iron Oxide Nanoparticles Against Escherichia coli

Autor: Mehrdad Khatami, Mohammad Reza Aflatoonian, Hakim Azizi, Farideh Mosazade, Ahmad Hooshmand, Marcos Augustino Lima Nobre, Farzad Minab Poodineh, Mansour Khatami, Sam Khraazi, Hadi Mirzaeei
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: International Journal of Basic Science in Medicine, Vol 2, Iss 4, Pp 166-169 (2017)
Druh dokumentu: article
ISSN: 2476-664X
DOI: 10.15171/ijbsm.2017.31
Popis: Introduction: Considering the usefulness of metal oxide nanoparticles in biology and biomedicine, iron oxide nanoparticles were biosynthesized using bioresource engineering to evaluate its antibacterial activity against Escherichia coli. Methods: Macrodilution method was used for calculating the lowest concentration which prevented the growth of bacteria (minimum inhibitory concentration [MIC]), and the lowest concentration that destroyed all bacterial cells (minimum bactericidal concentration [MBC]). Results: The lowest concentration of iron oxide nanoparticles that inhibited the growth of E. coli (MIC) was recorded at 250 µg/mL. On the other hand, the MBC of iron oxide nanoparticles was calculated at 500 µg/mL. Conclusion: Iron oxide nanoparticles were produced by a green and eco-friendly, simple and inexpensive method. The results showed the inhibitory effect of iron oxide nanoparticles on E. coli at 250 µg/mL. This may suggest using these nanoparticles as potential antibacterial agents.
Databáze: Directory of Open Access Journals