Biosensors for waterborne virus detection: Challenges and strategies

Autor: Xixi Song, Zina Fredj, Yuqiao Zheng, Hongyong Zhang, Guoguang Rong, Sumin Bian, Mohamad Sawan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Pharmaceutical Analysis, Vol 13, Iss 11, Pp 1252-1268 (2023)
Druh dokumentu: article
ISSN: 2095-1779
DOI: 10.1016/j.jpha.2023.08.020
Popis: Waterborne viruses that can be harmful to human health pose significant challenges globally, affecting health care systems and the economy. Identifying these waterborne pathogens is essential for preventing diseases and protecting public health. However, handling complex samples such as human and wastewater can be challenging due to their dynamic and complex composition and the ultralow concentration of target analytes. This review presents a comprehensive overview of the latest breakthroughs in waterborne virus biosensors. It begins by highlighting several promising strategies that enhance the sensing performance of optical and electrochemical biosensors in human samples. These strategies include optimizing bioreceptor selection, transduction elements, signal amplification, and integrated sensing systems. Furthermore, the insights gained from biosensing waterborne viruses in human samples are applied to improve biosensing in wastewater, with a particular focus on sampling and sample pretreatment due to the dispersion characteristics of waterborne viruses in wastewater. This review suggests that implementing a comprehensive system that integrates the entire waterborne virus detection process with high-accuracy analysis could enhance virus monitoring. These findings provide valuable insights for improving the effectiveness of waterborne virus detection, which could have significant implications for public health and environmental management.
Databáze: Directory of Open Access Journals