Value of SLE-DAS in assessing disease activity in patients with systemic lupus erythematosus: a single-centre retrospective study

Autor: Leixi Xue, Zhichun Liu, Lin Zhang, Jinlu Ma, Mengxue Yan
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Lupus Science and Medicine, Vol 11, Iss 1 (2024)
Druh dokumentu: article
ISSN: 2053-8790
DOI: 10.1136/lupus-2024-001196
Popis: Objectives This study aimed to evaluate the clinical value of the Systemic Lupus Erythematosus Disease Activity Score (SLE-DAS) for assessing disease activity in patients with SLE.Methods Clinical data were collected from patients with SLE who were admitted at the Second Affiliated Hospital of Soochow University from January 2009 to December 2022. The glucocorticoid dose grading was used as the gold standard for disease activity assessment in SLE. The SLE-DAS value was calculated, and the SLE disease activity status was graded based on the SLE-DAS value. Another scoring criterion, the SLE Disease Activity Index 2000 (SLEDAI 2000), served as a control. Spearman correlation analysis was used to calculate the correlation between the scoring criteria and other variables.Results The analysis included 396 patients with SLE. A strong correlation was found between SLE-DAS and SLEDAI 2000 (ρ=0.709, 95% CI 0.648 to 0.766, p
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