Advances in adeno-associated virus mediated gene therapy in tumors

Autor: YANG Xiao-juan, LI Zhen-hao, GOU Yuan-feng, HUO Xia-qin, PEI Ya-ping, LI Na, LIU Hui-ling
Jazyk: čínština
Rok vydání: 2021
Předmět:
Zdroj: Jichu yixue yu linchuang, Vol 41, Iss 4, Pp 573-577 (2021)
Druh dokumentu: article
ISSN: 1001-6325
Popis: Adeno-associated virus (AAV) is a human parvovirus with defects and no disease.AAV vector, as an ideal carrier for the transduction of target genes, has certain advantages in long-term gene correction and gene therapy by transferring foreign bases into cells by using the virus's capacity to infect cells.Due to its advantages of extensive host, strong safety and continuous expression of foreign genes, AAV has been used in gene therapy for a variety of tumor.
Databáze: Directory of Open Access Journals