Correlation between small and dense low‐density lipoprotein cholesterol and cardiovascular events in Beijing community population

Autor: Xiaona Wang, Liang Wang, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Ping Ye
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: The Journal of Clinical Hypertension, Vol 23, Iss 2, Pp 345-351 (2021)
Druh dokumentu: article
ISSN: 1751-7176
1524-6175
DOI: 10.1111/jch.14150
Popis: Abstract The relationship between small dense low‐density lipoprotein cholesterol (sdLDL‐C) and different cardiovascular events has been observed in several large community studies, and the results have been controversial. However, there is currently no cross‐sectional or longitudinal follow‐up study on sdLDL‐C in the Chinese hypertension population. We analyzed the association of plasma sdLDL‐C levels with major adverse cardiovascular events in 1325 subjects from a longitudinal follow‐up community‐based population in Beijing, China. During the follow‐up period, a total of 191 subjects had MACEs. Cox regression analysis showed that sdLDL‐C is a major risk factor for MACEs independent of sex, age, BMI, hypertension, diabetes, smoking, SBP, DBP, FBG, eGFR in the general community population (1.013 (1.001 −1.025, P
Databáze: Directory of Open Access Journals
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