Synthesis of Enantiomeric Halolactones with Aromatic Ring, Their Anticancer Activity and Interactions with Biological Membranes

Autor: Witold Gładkowski, Aleksandra Pawlak, Aleksandra Włoch, Marcelina Mazur, Halina Kleszczyńska, Bożena Obmińska-Mrukowicz
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Proceedings, Vol 22, Iss 1, p 47 (2019)
Druh dokumentu: article
ISSN: 2504-3900
20190220
DOI: 10.3390/proceedings2019022047
Popis: Studying the effect of chirality on the activity of tested compounds, we synthesized new series of the enantiomeric (ee = 98–100%) β-aryl-δ-halo-γ-lactones with defined configurations of stereogenic centers. [...]
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