| Autor: |
Daniel eGrasso, Maria Ines Vaccaro |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Frontiers in Endocrinology, Vol 5 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1664-2392 |
| DOI: |
10.3389/fendo.2014.00157 |
| Popis: |
The oncogene-induced senescence is emerging as a potent tumor suppressor mechanism and as a possible therapeutic target. Macroautophagy is intimately linked to the senescence condition setup, although its role has not been elucidated yet. Here we discuss up-to-date concepts of senescence-related macroautophagy and evaluate the current trend of this growing research field, which has relevance in future perspectives towards therapeutic options against cancer. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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