Biologicals for pediatric patients with atopic dermatitis: practical challenges and knowledge gaps

Autor:	Lisa P. van der Rijst, Annet van Royen-Kerkhof, Suzanne G. M. A. Pasmans, Renske Schappin, Marjolein S. de Bruin-Weller, Marlies de Graaf
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	atopic dermatitis biological therapy pediatric dermatology immunomodulating therapy children Dermatology RL1-803
Zdroj:	Journal of Dermatological Treatment, Vol 34, Iss 1 (2023)
Druh dokumentu:	article
ISSN:	0954-6634 1471-1753 09546634
DOI:	10.1080/09546634.2023.2254567
Popis:	Biologicals are becoming increasingly important in the therapeutic landscape of pediatric patients with moderate-to-severe atopic dermatitis (AD). Currently, dupilumab and tralokinumab are registered for the treatment of moderate-to-severe AD, and novel biologicals are expected to follow. Dupilumab was the first biological registered for AD in pediatric patients and was recently approved for patients aged six months to five years. Current and emerging biologicals may address the unmet need for effective and safe treatment options for pediatric AD patients, however, little is known about the practical implementation of biologicals in infants and preschoolers (aged
Databáze:	Directory of Open Access Journals
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