Rickettsia felis: A Review of Transmission Mechanisms of an Emerging Pathogen

Autor: Kelsey P. Legendre, Kevin R. Macaluso
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Tropical Medicine and Infectious Disease, Vol 2, Iss 4, p 64 (2017)
Druh dokumentu: article
ISSN: 2414-6366
DOI: 10.3390/tropicalmed2040064
Popis: Rickettsia felis is an emerging pathogen of the transitional group of Rickettsia species and an important cause of febrile illness in Africa. Since the organism’s original discovery in the early 1990s, much research has been directed towards elucidating transmission mechanisms within the primary host and reservoir, the cat flea (Ctenocephalides felis). Several mechanisms for vertical and horizontal transmission within this vector have been thoroughly described, as well as transmission to other arthropod vectors, including other species of fleas. However, while a growing number of human cases of flea-borne spotted fever are being reported throughout the world, a definitive transmission mechanism from arthropod host to vertebrate host resulting in disease has not been found. Several possible mechanisms, including bite of infected arthropods and association with infectious arthropod feces, are currently being investigated.
Databáze: Directory of Open Access Journals