Prognostic factors of overall survival for patients with stage II colon cancer

Autor: Harsha Trivedi, Ushasree Chamarthy, Luciano Dicarlo, James Herman, Gordan Srkalovic
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Acta Medica Academica, Vol 43, Iss 2, Pp 134-143 (2014)
Druh dokumentu: article
ISSN: 1840-1848
DOI: 10.5644/ama2006-124.112
Popis: Objective. To analyze factors influencing survival of patients with stage II colon cancer treated at our cancer center (Sparrow Hospital) from February 1996 through December 2006. Patients and methods. Survival analyses on 197 patients’ age 71.1±0.9 years (29 to 97) were done using SAS system (V9.3, Cary NC). Analysis included age, gender, stage, surgery type, number of examined lymph nodes, pathological grade, tumor size and the use of adjuvant chemotherapy. Results. Mean follow up length was 48.1±2.3 months (0.1-133) and 56±3.3 (0.2-133) for survivors. The average number of removed lymph nodes was 18±13 (1-103). Adjuvant chemotherapy treatment (5-FU± leucovorin) was given to 49 patients, while others (148) were followed expectantly. There were 90 deaths during follow up. Only age exhibits a statistically significant relationship to survival (Hazard Ratio (HR) =1.06, 95% CI=1.03-1.08, p
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