Soypeptide supplementation attenuates weight loss and improves quality of life among brain cancer patients in a pilot study

Autor: William Kwame Amakye, Chujun Huang, Zhenzhen Xu, Min Wang, Ji Guo, Yonggao Mou, Chengcheng Guo, Qunying Yang, Fang Ma, Suyun Li, Desmond Omane Acheampong, Christiana Nsiah‐Asamoah, Jessica Ayensu, Nana Ama Frimpomaa Agyapong, Erdong Yuan, Maojin Yao, Jiaoyan Ren
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Food Frontiers, Vol 4, Iss 3, Pp 1298-1310 (2023)
Druh dokumentu: article
ISSN: 2643-8429
DOI: 10.1002/fft2.242
Popis: Abstract Inability to meet nutrition needs resulting from multiple diseases‐related, and individual factors contribute significantly to malnutrition and poor disease outcome among cancer patients. Strategies capable of delivering metabolically efficient nutrients with less digestive and metabolic stress without adding bulk to the diet of patients may be suitable for dealing with cancer‐related malnutrition and quality of life (QoL). We sought to test the hypothesis that peptide supplementation could attenuate weight loss and improve QoL among brain cancer patients compared to conventionally treated controls. In a non‐blind pilot study, brain cancer patients received 9 g soybean peptide supplementation twice per day (peptide group, n = 9) and compared with conventional treatment (control group, n = 10) over two chemotherapy cycles of 42 days. Compared to the controls, soypeptide supplementation attenuated weight loss with 5.4% increase in weight. Moreover, QoL, assessed using the European Organization for Research and Treatment of Cancer QLQ‐C30, revealed that physical (8.1 ± 15.6, p
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