Myelin oligodendrocyte glycoprotein antibody titers by fixed cell-based assay: positive predictive value and impact of sample collection timing

Autor: Adrian Budhram, Dalia L. Rotstein, Liju Yang, E. Ann Yeh
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Neurology, Vol 15 (2024)
Druh dokumentu: article
ISSN: 1664-2295
46704612
DOI: 10.3389/fneur.2024.1380541
Popis: IntroductionIn January 2023, our laboratory began performing serum myelin oligodendrocyte glycoprotein antibody (anti-MOG) titers by fixed cell-based assay (CBA). As a quality assurance (QA) assessment, we evaluated titer positive predictive value (PPV) as well as impact of sample collection timing on titers.MethodsAmong patients who underwent antibody titers to distinguish between low-positive (
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