Associations Between Reductions in Depressive Symptoms and Reductions in Pain and Anxiety Symptoms and Substance Use: Emulation of a Randomized Trial

Autor: Maria R. Khan, PhD, MPH, Mary Acri, PhD, Kaoon (Francois) Ban, MPH, Joy D. Scheidell, PhD, MPH, Elizabeth R. Stevens, PhD, MPH, Prima Manandhar-Sasaki, MSc, Dyanna Charles, MPH, Natalie E. Chichetto, PhD, MSW, Stephen Crystal, PhD, Adam J. Gordon, MD, MPH, Brandon D.L. Marshall, PhD, E. Jennifer Edelman, MD, MHS, Amy C. Justice, MD, PhD, Scott R. Braithwaite, MD, MS, Ellen C. Caniglia, ScD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: AJPM Focus, Vol 3, Iss 5, Pp 100258- (2024)
Druh dokumentu: article
ISSN: 2773-0654
DOI: 10.1016/j.focus.2024.100258
Popis: Introduction: Depressive symptoms are linked with pain, anxiety, and substance use. Research estimating whether a reduction in depressive symptoms is linked to subsequent reductions in pain and anxiety symptoms and substance use is limited. Methods: Using data from the Veterans Aging Cohort Study, a multisite observational study of U.S. veterans, the authors used a target trial emulation framework to compare individuals with elevated depressive symptoms (Patient Health Questionnaire-9 score ≥ 10) who experienced reductions in depressive symptoms (Patient Health Questionnaire-9 score
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