Repeated daily dosing of weekly methotrexate therapy causing multiorgan toxicity: a case report
| Autor: | Emma Davey, Geoffrey K. Isbister |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Toxicology Communications, Vol 7, Iss 1 (2023) |
| Druh dokumentu: | article |
| ISSN: | 24734306 2473-4306 |
| DOI: | 10.1080/24734306.2023.2221508 |
| Popis: | AbstractMethotrexate toxicity following intravenous (IV) methotrexate is well reported, but there is less information on accidental daily dosing of a prescribed weekly dose of oral methotrexate. A 70 year old female presented following accidentally taking 20 mg methotrexate for five days, with multiple oral ulcers, thrombocytopenia (platelets 80 x 109/L [reference range[RR]:150-400 x 109/L]) and an alanine aminotransferase 820 U/L [RR:10-35 U/L]. Methotrexate was undetectable [ |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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