Efficacy of Topical 0.05% Isotretinoin Gel Versus 0.1% Adapalene Gel in The Treatment of Mild to Moderate Acne Vulgaris
| Autor: | Summaya Saleem, Naeem Raza, Nida Saleem, Saleem Ullah, Ghazala Yasmin, Farrah Yousaf |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Pakistan Armed Forces Medical Journal, Vol 73, Iss 1 (2023) |
| Druh dokumentu: | article |
| ISSN: | 0030-9648 2411-8842 |
| DOI: | 10.51253/pafmj.v73i1.6472 |
| Popis: | Objective: To compare the efficacy of topical 0.05% Isotretinoin gel versus 0.1% Adapalene gel in treating mild to moderate acne vulgaris. Study Design: Quasi-Experimental study. Place and Duration of Study: Department of Dermatology, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, From Feb to Jul 2018. Methodology: A total of ninety-two patients aged 12 to 25 years with mild to moderate facial acne vulgaris were enrolled and divided into two treatment Groups, Group-A (0.05% Isotretinoin Gel) and Group-B (0.1% Adapalene Gel). Efficacy was measured at 12 weeks post-treatment. Results: Treatment was found efficacious in 84.8% (n=39/46) of patients in Group-A and 50.0% (n=23/46) of patients in Group-B (p= 0.001). There were similar results when treatment efficacy in both Groups was disease severity. In all cases,efficacy was better in Group-A (p |
| Databáze: | Directory of Open Access Journals |
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