The predictive role of aortic propagation velocity for coronary artery disease

Autor: Fereshteh Ghaderi, Hossein Samim, Faeze Keihanian, Seyed Ali Danesh Sani
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: BMC Cardiovascular Disorders, Vol 18, Iss 1, Pp 1-7 (2018)
Druh dokumentu: article
ISSN: 1471-2261
DOI: 10.1186/s12872-018-0854-9
Popis: Abstract Background It is well recognized that cardio- vascular risk factors lead to histological and functional changes in aorta, and aortic stiffness is the best predictor of cardiovascular morbidity and mortality. In this study we evaluated the relation of a less evaluated echocardiographic parameter of aortic stiffness, aortic propagation velocity (APV) with the presence and severity of CAD. Methods This cross sectional study was conducted from May 2015 to March 2016 in Imam Reza hospital, Mashhad, Iran. Seventy patients who were referred for elective coronary artery angiography were enrolled. Patients were divided into two sub-groups based on angiographic findings: patients with CAD (38 patients, 54.3%) and non-CAD (32 patients, 45.7%). Transthoracic echocardiography was performed using the conventional 2D and color M-Mode imaging. Aortic propagation velocity (APV), aortic strain (AS) and distensibility (AD) were measured. The presence and Severity of CAD (assessing by syntax score) and their relation with aortic stiffness indices were assessed. Results Aortic strain (6.23 ± 1.93% versus 11.66 ± 4.86%, P
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