The Relationship of Staphylococcus aureus Virulancity with Serum Cytokine Levels in Polycystic Ovary Syndrome and Polycystic Ovary Disease

Autor: AL-Khafaji Rana Jaleil, Al-Fatlawi Basaad Abed Zaid, Al-Mamory Al-Mamory Abdulnabi Jwaid
Jazyk: English<br />French
Rok vydání: 2024
Předmět:
Zdroj: BIO Web of Conferences, Vol 108, p 04018 (2024)
Druh dokumentu: article
ISSN: 2117-4458
DOI: 10.1051/bioconf/202410804018
Popis: The current study was done to isolation and indentification of the Staphlococcus aureus isolates associated with polycystic ovarian syndrome patients and determine the immunological status for these patients. Inflammatory markers have been linked to polycystic ovary syndrome (PCOS). Because ovulation is a quasi-inflammatory process, endothelial adipose tissue can stimulate an inflammatory response and maintain inflammation in adipocytes. By influencing the release of inflammatory cytokines from this downregulated inflammation, polycystic ovary syndrome can arise. The study included 105 clinical specimens, that include age (20-45) years which were collected from November 2022 to June 2023. The specimens included blood specimens and vaginal swabs. They visit Imam Al-Sadiq Hospital and Babylon Teaching Hospital for Maternity and Children in Babylon Governorate. The results of vaginal swabs culture, biochemical tests and vitic2 for isolated bacteria from patients were revealed that Gram-positive bacteria isolates were dominant, amounting to 51 (54.83%), while the percentage of Gram-negative bacteria was 37 (39.78%), while fungi percentage was 5 (5.37%). The results showed that Staphylococcus aureus is the most common bacteria among Gram-positive bacteria, as it constituted 38 (40.86%), followed by Lactobacillus spp. As it accounted for 11 (11.82%) of Staphylococcus epidermidis by 2 (2.15%). The Gram-negative isolates included Escherichiae coli, Klebsiella pneumoniae, and Pseudomonase aerogenosa 23 (24.73%), 9(9.67%) and 5 (5.37%), respectively also the result demonstrates that IL-10, IL-13 level significantly elevation in PCOS, PCOD patients group.
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