Levofloxacin prophylaxis for pediatric leukemia patients: monitoring of outcomes for sustained benefit and consequences

Autor: Andrea L. Davis, Alexandra M. Stevens, Julienne Brackett, Lucila Marquez, Catherine E. Foster, Adriana Sarmiento Clemente, Hannah E. Sauer, Grant T. Stimes, Judith R. Campbell
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Antimicrobial Stewardship & Healthcare Epidemiology, Vol 4 (2024)
Druh dokumentu: article
ISSN: 2732-494X
DOI: 10.1017/ash.2024.81
Popis: Levofloxacin prophylaxis reduces bloodstream infections in neutropenic patients with acute myeloid leukemia or relapsed acute lymphoblastic leukemia. A retrospective, longitudinal cohort study compares incidence of bacteremia, multidrug-resistant organisms (MDRO), and Clostridioides difficile (CDI) between time periods of levofloxacin prophylaxis implementation. Benefits were sustained without increasing MDRO or CDI.
Databáze: Directory of Open Access Journals