Retroperitoneal Robot-assisted Partial Nephrectomy: A Systematic Review and Pooled Analysis of Comparative Outcomes

Autor: Umberto Carbonara, Fabio Crocerossa, Riccardo Campi, Alessandro Veccia, Giovanni E. Cacciamani, Daniele Amparore, Enrico Checcucci, Davide Loizzo, Angela Pecoraro, Michele Marchioni, Chiara Lonati, Chandru P. Sundaram, Reza Mehrazin, James Porter, Jihad H. Kaouk, Francesco Porpiglia, Pasquale Ditonno, Riccardo Autorino
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: European Urology Open Science, Vol 40, Iss , Pp 27-37 (2022)
Druh dokumentu: article
ISSN: 2666-1683
DOI: 10.1016/j.euros.2022.03.015
Popis: Context: Robot-assisted partial nephrectomy (RAPN) has gained increasing popularity as primary minimally invasive surgical treatment for localized renal tumors, and it has preferably been performed with a transperitoneal approach. However, the retroperitoneal approach represents an alternative approach given potential advantages. Objective: To provide an updated analysis of the comparative outcomes of retroperitoneal RAPN (R-RAPN) versus transperitoneal RAPN (T-RAPN). Evidence acquisition: A systematic review of the literature was performed up to September 2021 using MEDLINE, EMBASE, and Web of Science databases, according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) recommendations. A sensitivity analysis was performed considering only matched-pair studies. Evidence synthesis: Seventeen studies, which were published between 2013 and 2021, were retrieved. None of them was a randomized clinical trial. Among the 6,266 patients included in the meta-analysis, 2261 (36.1%) and 4,005 (63.9%) underwent R-RAPN and T-RAPN, respectively. No significant difference was found in terms of baseline features. The T-RAPN group presented a higher rate of male patients (odds ratio [OR]: 0.86, p = 0.03) and larger tumor size (weighted mean difference [WMD]: 0.2 cm; p = 0.003). The R-RAPN group reported more frequent posterior renal masses (OR: 0.23; p
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