Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients

Autor:	Ali Abdul Hussein S Al-Janabi
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	psa chronic kidney failure prostate renal dialysis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Asian Journal of Oncology, Vol 07, Iss 02, Pp 082-084 (2021)
Druh dokumentu:	article
ISSN:	2454-6798 2455-4618
DOI:	10.1055/s-0041-1729346
Popis:	Introduction Prostate-specific antigen (PSA) is a biomarker commonly used for detection of prostate cancer. Its viability as a marker for diagnosis of chronic renal failure (CRF) in predialysis patients was investigated. Methods Sera from 230 patients with CRF were analyzed by enzyme-linked immunosorbent assay (ELISA) for determining total PSA (tPSA) levels before hemodialysis. Results Of the patients investigated, 98.69% had a normal PSA level with a value less than 4 ng/mL. Three elderly men with both kidney failure showed a moderate elevation of PSA level. Conclusion PSA is considered a nonsignificant indicator for diagnosis of CRF.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/64b1acbe91b44146a7edd0b42897da31 Zobrazit plný text záznamu View record in DOAJ