Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the country

Autor: Danilo Alves de França, Filipe Pereira da Silva, Dayane da Silva Zanini, Lorena Iglesias, Laura Portillo, Herminia Cortez, Alexander Welker Biondo, Ana Íris de Lima Duré, Marcos Vinicius Ferreira Silva, Jorge Miret, Helio Langoni
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: One Health, Vol 18, Iss , Pp 100660- (2024)
Druh dokumentu: article
ISSN: 2352-7714
DOI: 10.1016/j.onehlt.2023.100660
Popis: Coxiella burnetii is the agent of Q fever, a disease that poses risks to public health and damages livestock. We discovered the circulation of C. burnetii for the first time in Paraguay, based on the seropositivity of a flock of >300 sheep. The animals were tested by IFA for anti-C. burnetii antibodies and by SAM for anti-Leptospira spp. antibodies, an important differential diagnosis for reproductive disorders in sheep in Paraguay. C. burnetii seropositivity was determined in 45%, in contrast to Leptospira spp. which had no reactive samples. Cases of miscarriage and fetal resorption were associated with high seropositivity titers. This study suggests the circulation of a unique genotype in the country and an imminent risk to public health, since in addition to being highly transmissible and infectious to humans, Q fever is still not a cause for concern on the part of government and health agencies in the country.
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