Effect of gamma irradiation on filtering facepiece respirators and SARS-CoV-2 detection

Autor: Khaled Al-Hadyan, Ghazi Alsbeih, Najla Al-Harbi, Sara Bin Judia, Maha Al-Ghamdi, Akram Almousa, Ibtihaj Alsharif, Razan Bakheet, Khaldoun Al-Romaih, Maha Al-Mozaini, Salem Al-Ghamdi, Belal Moftah, Rashed Alhmaid
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-021-99414-6
Popis: Abstract To cope with the shortage of filtering facepiece respirators (FFRs) during the coronavirus (COVID-19) pandemic, healthcare institutions were forced to reuse FFRs after applying different decontamination methods including gamma-irradiation (GIR). The aim of this study was to evaluate the effect of GIR on the filtration efficiency (FE) of FFRs and on SARS-CoV-2 detection. The FE of 2 FFRs types (KN95 and N95-3 M masks) was assessed at different particle sizes (0.3–5 µm) following GIR (0–15 kGy) delivered at either typical (1.65 kGy/h) or low (0.5088 kGy/h) dose rates. The detection of two SARS-CoV-2 RNA genes (E and RdRp4) following GIR (0–50 kGy) was carried out using RT-qPCR assay. Both masks showed an overall significant (P
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