| Autor: |
Mohsina Khan, Arun Vaidyanath, Deepika Suresh, Bhumika Vaishnav, Arjun Lal Kakrani, Swapnil Patil, Anjali Shiras |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Stem Cell Research, Vol 42, Iss , Pp - (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1873-5061 |
| DOI: |
10.1016/j.scr.2019.101678 |
| Popis: |
Three induced pluripotent stem cells (iPSC) clones NCCSi007-A, NCCSi007-B and NCCSi007-C were generated from CD4+T cells of a 38 years old male patient suffering from liver cirrhosis- alcoholic and minimal hepatic encephalopathy of Indian origin. The CD4+T cells of the patient were reprogrammed using integration free, Sendai viral vector system. Each of the three iPSC clones showed high alkaline phosphatase (ALP) activity, expressed pluripotency markers OCT4, SOX2, NANOG, KLF4, SSEA-4, TRA-1–60, showed normal male karyotype (46, XY) and exhibited multi-lineage differentiation. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
