Liver Cholestasis Secondary to Syphilis in an Immunocompetent Patient

Autor: Nazneen Hussain, Samuel O. Igbinedion, Richie Diaz, J. S. Alexander, Moheb Boktor, Kurt Knowles
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Case Reports in Hepatology, Vol 2018 (2018)
Druh dokumentu: article
ISSN: 2090-6587
2090-6595
DOI: 10.1155/2018/8645068
Popis: Liver involvement is a known feature of secondary syphilis. The prevalence of hepatitis in secondary syphilis ranges broadly from 1 to 50%. We report a case of a 37-year-old man with type 1 diabetes mellitus and sickle cell trait presenting with jaundice and acute liver cholestasis. Abdominal ultrasound revealed mild hepatic fatty infiltration. RPR and Treponema pallidum IgG results were positive with a reflex titer of 1:64. Liver biopsy revealed chronic hepatitis with normal hepatic architecture, Kupffer cell hyperplasia, hepatic cholestasis, and ductal proliferation suggestive of syphilitic hepatitis.
Databáze: Directory of Open Access Journals
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