Progressive divisions of multipotent neural progenitors generate late-born chandelier cells in the neocortex

Autor: Khadeejah T. Sultan, Wenying Angela Liu, Zhao-Lu Li, Zhongfu Shen, Zhizhong Li, Xin-Jun Zhang, Owen Dean, Jian Ma, Song-Hai Shi
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-07055-7
Popis: Diverse GABAergic neurons arise from progenitors in the medial ganglionic eminence. Here, the authors show these progenitors are progressively fate-restricted, with early-born interneurons occupying cortex in an “inside-out” pattern and later-born types like chandelier cells generated “outside-in”.
Databáze: Directory of Open Access Journals