Investigation of histological heterogeneity based on the discrepancy between the hyperintense area on T2-weighted images and the accumulation area on 11C-methionine PET in minimally enhancing glioma

Autor: Makoto Ideguchi, Takafumi Nishizaki, Norio Ikeda, Natsumi Fujii, Machiko Ohno, Taichi Shimabukuro, Tokuhiro Kimura, Eiji Ikeda, Kazuyoshi Suga
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Interdisciplinary Neurosurgery, Vol 27, Iss , Pp 101364- (2022)
Druh dokumentu: article
ISSN: 2214-7519
DOI: 10.1016/j.inat.2021.101364
Popis: Introduction: The objective of the study was to investigate the correlation between differences between imaging modalities and histological heterogeneity in minimally enhancing glioma. Methods: A prospective study was performed in 11 patients with minimally enhancing glioma (10%. The correlation between the imaging discrepancy and histological heterogeneity was investigated. Results: The average T/N ratio for the T2/FL+/MET+ area in grade II glioma (2.08 ± 0.4) was smaller than that in grade III (4.19 ± 2.4), whereas that for the T2/FL+/MET− area was similar in grade II (1.07 ± 0.2) and III (1.07 ± 0.1). The average T/N ratio for the T2/FL+/MET+ area in grade II and III was higher than that for the T2/FL+/MET− area (p
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