Sarcoidosis and lymphoma mortality risk: An observational study from the Spanish National Registry

Autor: Víctor Moreno-Torres, María Martínez-Urbistondo, Pedro Durán-del Campo, Pablo Tutor, Begoña Rodríguez, Raquel Castejón, Susana Mellor-Pita
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Translational Autoimmunity, Vol 8, Iss , Pp 100236- (2024)
Druh dokumentu: article
ISSN: 2589-9090
DOI: 10.1016/j.jtauto.2024.100236
Popis: Introduction: Patients with sarcoidosis have a lower survival rate than the general population, in part due to cardiovascular disease, infections and neoplasms. Our objective was to evaluate the impact of haematological neoplasms (HN) and lymphomas on sarcoidosis patient mortality in a nation-wide analysis conducted in Spain, a country with a population of 47 million. Methods: Retrospective and observational comparison of the HN related deaths in sarcoidosis patients and the general Spanish population reported in the Spanish Hospital Discharge Database. To determine the impact of sarcoidosis on the risk of dying from each HN lineage, a binary logistic regression considering age, female sex, tobacco and alcohol consumption, was performed. Results: In the period 2016 and 2019, 139,531 in-hospital deaths from neoplasms were certified in Spain (77 in patients with sarcoidosis). Patients with sarcoidosis died at younger age than the general Spanish population (72.9 vs 77.6, p
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