| Autor: |
Tomas Escobar Gil, Mohammed A. Quazi, Tushita Verma, Amir H. Sohail, Hafiz Abdullah Ikram, Adeel Nasrullah, Karthik Gangu, Asif Farooq, Abu Baker Sheikh |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Geriatrics, Vol 9, Iss 1, p 7 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2308-3417 |
| DOI: |
10.3390/geriatrics9010007 |
| Popis: |
Previous studies have convincingly demonstrated the negative impact of dementia on overall health outcomes. In the context of the COVID-19 pandemic, there is burgeoning evidence suggesting a possible association between dementia and adverse outcomes, however the relationship has not been conclusively established. We conducted a retrospective cohort study involving 816,960 hospitalized COVID-19 patients aged 65 or older from the 2020 national inpatient sample. The cohort was bifurcated into patients with dementia (n = 180,845) and those without (n = 636,115). Multivariate regression and propensity score matched analyses (PSM) assessed in-hospital mortality and complications. We observed that COVID-19 patients with dementia had a notably higher risk of in-hospital mortality (23.1% vs. 18.6%; aOR = 1.2 [95% CI 1.1–1.2]). This elevated risk persisted even after PSM. Interestingly, dementia patients had a reduced risk of several acute in-hospital complications, including liver failure and sudden cardiac arrest. Nevertheless, they had longer hospital stays and lower total hospital charges. Our findings conclusively demonstrate that dementia patients face a heightened risk of mortality when hospitalized with COVID-19 but are less likely to experience certain complications. This complexity underscores the urgent need for individualized care strategies for this vulnerable group. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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