Prognostic value of morphology and hemodynamics in moyamoya disease for long-term outcomes and disease progression

Autor: Long Ma, Peicong Ge, Chaofan Zeng, Chenglong Liu, Zihan Yin, Xiaolong Ya, Yuanren Zhai, Qiheng He, Junsheng Li, Xun Ye, Qian Zhang, Rong Wang, Dong Zhang, Yan Zhang, Jizong Zhao
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-024-79608-4
Popis: Abstract To explore the relationship between morphological and hemodynamic parameters, baseline characteristics, and long-term outcomes in patients with moyamoya disease (MMD) using a computational fluid dynamics model. We retrospectively reviewed 129 patients at Beijing Tiantan hospital between July 2020 and December 2021. Perioperative clinical variables and Suzuki stage were recorded. Logistic regression analysis was employed to identify the risk factors for unfavorable long-term outcomes. The association between morphological, CT perfusion parameters, hemodynamic parameters and the Suzuki stage, clinical variables of MMD was also analyzed. Patients with high relative Wall Shear Stress (rWSS) were older and had more cases with higher Suzuki stage and worse follow-up mRS scores (p
Databáze: Directory of Open Access Journals
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