The effects of pulsatile versus nonpulsatile flow on cerebral pulsatility index, mean flow velocity at the middle cerebral artery, regional cerebral oxygen saturation, cerebral gaseous microemboli counts, and short-term clinical outcomes in patients undergoing congenital heart surgeryCentral MessagePerspective

Autor: Krishna Patel, BS, Yongwook Dan, MD, Allen R. Kunselman, MA, Joseph B. Clark, MD, John L. Myers, MD, Akif Ündar, PhD
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: JTCVS Open, Vol 16, Iss , Pp 786-800 (2023)
Druh dokumentu: article
ISSN: 2666-2736
DOI: 10.1016/j.xjon.2023.08.013
Popis: Objective: The objective of this retrospective review was to evaluate whether or not pulsatile flow improves cerebral hemodynamics and clinical outcomes in pediatric congenital cardiac surgery patients. Methods: This retrospective study included 284 pediatric patients undergoing congenital cardiac surgery with cardiopulmonary bypass support utilizing nonpulsatile (n = 152) or pulsatile (n = 132) flow. Intraoperative cerebral gaseous microemboli counts, pulsatility index, and mean blood flow velocity at the right middle cerebral artery were assessed using transcranial Doppler ultrasound. Clinical outcomes were compared between groups. Results: Patient demographics and cardiopulmonary bypass characteristics between groups were similar. Although the pulsatility index during aortic crossclamping was consistently higher in the pulsatile group (P
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