Altano-axial subluxation with torticollis secondary to Langerhans cell histocytosis

Autor: Joshua Y. Chua, MD, Ji Min Ling, FRCS, Derrick W.Q. Lian, FRCPath, Mei Yoke Chan, FRCP, David C.Y. Low, FRCS, Sharon Y.Y. Low, PhD, FRCS
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Interdisciplinary Neurosurgery, Vol 10, Iss , Pp 101-103 (2017)
Druh dokumentu: article
ISSN: 2214-7519
DOI: 10.1016/j.inat.2017.07.015
Popis: Langerhans Cell Histiocytosis is a rare disease featuring aberrant proliferation of dendritic cells that can infiltrate the bony skeleton. The authors report a case of six-year-old female presenting with torticollis. She was found to have extensive lytic LCH lesions in the cranio-cervical junction, causing atlanto-axial rotatory subluxation. Decision was made for a non-surgical approach to treat the patient. She was placed in a Halo brace, and given concomitant chemotherapy. Post-treatment imaging demonstrated near-complete reconstitution of the skeleton affected by LCH. This case highlights the feasibility of non-surgical treatment in selected LCH patients at high-risk of spinal instability. Keywords: Atlanto-axial subluxation, Langerhans cell histocytosis, Torticollis
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