Use of Digital Technology Tools to Characterize Adherence to Prescription-Grade Omega-3 Polyunsaturated Fatty Acid Therapy in Postmyocardial or Hypertriglyceridemic Patients in the DIAPAsOn Study: Prospective Observational Study

Autor: Gregory P Arutyunov, Alexander G Arutyunov, Fail T Ageev, Tatiana V Fofanova
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: JMIR Cardio, Vol 6, Iss 2, p e37490 (2022)
Druh dokumentu: article
ISSN: 2561-1011
DOI: 10.2196/37490
Popis: BackgroundMaintaining sustained adherence to medication for optimal management of chronic noninfectious diseases, such as atherosclerotic vascular disease, is a well-documented therapeutic challenge. ObjectiveThe DIAPAsOn study was a 6-month, multicenter prospective observational study in the Russian Federation that examined adherence to a preparation of highly purified omega-3 polyunsaturated fatty acids (Omacor) in 2167 adult patients with a history of recent myocardial infarction or endogenous hypertriglyceridemia. MethodsA feature of DIAPAsOn was the use of a bespoke electronic patient engagement and data collection system to monitor adherence. Adherence was also monitored by enquiry at clinic visits. A full description of the study’s aims and methods has appeared in JMIR Research Protocols. ResultsThe net average reduction from baseline in both total and low-density lipoprotein cholesterol was approximately 1 mmol/L and the net average increase in high-density lipoprotein cholesterol was 0.2 (SD 0.53) mmol/L (P
Databáze: Directory of Open Access Journals