Diagnosis of comorbid migraine without aura in patients with idiopathic/genetic epilepsy based on the gray zone approach to the International Classification of Headache Disorders 3 criteria

Autor: Arife Çimen Atalar, Aynur Özge, Bengi Gül Türk, Esme Ekizoğlu, Duygu Kurt Gök, Betül Baykan, Semih Ayta, Füsun Ferda Erdoğan, Seher Naz Yeni, Bahar Taşdelen, IDEM Study Group, Sibel K. Velioğlu, Zuhal Yapıcı, İpek Midi, Saygı Serap, Çelebi Ulufer, Elif Sarıca Darol, Kadriye Ağan, Senem Ayç, Sibel Gazioğlu, Zeynep Vildan Okudan, Nermin Görkem Şirin, Nerses Bebek, Neşe Dericioğlu, İlknur Güçlü Altun, Ayşe Destina Yalçın, Reyhan Sürmeli, Oğuz Osman Erdinç, Abidin Erdal, Demet İlhan Algın, Gülnihal Kutlu, Semai Bek, Yüksel Erdal, Akçay Övünç Özön, Aylin Reyhani, Babürhan Güldiken, Barış Baklan, Bülent Oğuz Genç, Ebru Aykutlu Altindağ, Gökçen Karahan, Güray Koç, Handan Mısırlı, İbrahim Öztura, Kezban Aslan-Kara, Melodi Çakar Merve, Nur Türkmen, Onur Bulut, Karadaş Ömer, Özlem Kesim Çahin, Sevgi Ferik, Taylan Peköz Mehmet, Pınar Topaloğlu, Sibel Üstün Özek, Ülkühan Düzgün, Vildan Yayla, Yasemin Gömceli, Zeynep Ünlüsoy Acar
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Neurology, Vol 13 (2023)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2022.1103541
Popis: BackgroundMigraine without aura (MwoA) is a very frequent and remarkable comorbidity in patients with idiopathic/genetic epilepsy (I/GE). Frequently in clinical practice, diagnosis of MwoA may be challenging despite the guidance of current diagnostic criteria of the International Classification of Headache Disorders 3 (ICHD-3). In this study, we aimed to disclose the diagnostic gaps in the diagnosis of comorbid MwoA, using a zone concept, in patients with I/GEs with headaches who were diagnosed by an experienced headache expert.MethodsIn this multicenter study including 809 consecutive patients with a diagnosis of I/GE with or without headache, 163 patients who were diagnosed by an experienced headache expert as having a comorbid MwoA were reevaluated. Eligible patients were divided into three subgroups, namely, full diagnosis, zone I, and zone II according to their status of fulfilling the ICHD-3 criteria. A Classification and Regression Tree (CART) analysis was performed to bring out the meaningful predictors when evaluating patients with I/GEs for MwoA comorbidity, using the variables that were significant in the univariate analysis.ResultsLonger headache duration (
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