| Autor: |
Sina A. Tegethoff, Guy Danziger, Dennis Kühn, Charlotte Kimmer, Thomas Adams, Lena Heintz, Carlos Metz, Katharina Reifenrath, Rebecca Angresius, Sebastian Mang, Torben Rixecker, André Becker, Jürgen Geisel, Christophe Jentgen, Frederik Seiler, Matthias C. Reichert, Franziska Fröhlich, Sascha Meyer, Jürgen Rissland, Sebastian Ewen, Gudrun Wagenpfeil, Katharina Last, Sigrun Smola, Robert Bals, Frank Lammert, Sören L. Becker, Marcin Krawczyk, Philipp M. Lepper, Cihan Papan |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
International Journal of Infectious Diseases, Vol 122, Iss , Pp 178-187 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1201-9712 |
| DOI: |
10.1016/j.ijid.2022.05.051 |
| Popis: |
ABSTRACT: Background: Early prognostication of COVID-19 severity will potentially improve patient care. Biomarkers, such as TNF-related apoptosis-inducing ligand (TRAIL), interferon gamma-induced protein 10 (IP-10), and C-reactive protein (CRP), might represent possible tools for point-of-care testing and severity prediction. Methods: In this prospective cohort study, we analyzed serum levels of TRAIL, IP-10, and CRP in patients with COVID-19, compared them with control subjects, and investigated the association with disease severity. Results: A total of 899 measurements were performed in 132 patients (mean age 64 years, 40.2% females). Among patients with COVID-19, TRAIL levels were lower (49.5 vs 87 pg/ml, P = 0.0142), whereas IP-10 and CRP showed higher levels (667.5 vs 127 pg/ml, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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