Role of serial urine sediment examination in progression and outcome of sepsis-associated acute kidney injury
| Autor: | Mohamed Mamdouh Elsayed, Ahmed Elsayed Eldeeb, Mona Moustafa Tahoun, Hala Saddik ElWakil, Salah Saeed Naga |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Alexandria Journal of Medicine, Vol 60, Iss 1, Pp 312-318 (2024) |
| Druh dokumentu: | article |
| ISSN: | 20905068 2090-5076 2090-5068 |
| DOI: | 10.1080/20905068.2024.2393441 |
| Popis: | Introduction Sepsis-associated acute kidney injury (SA-AKI) is common in hospitalized patients. There is a rising interest in validating new tools for predicting its prognosis and outcome. We aimed to assess the role of serial urine sediment examination in the progression and outcome of SA-AKI.Material and Methods This research is a prospective study which included 80 patients with SA-AKI stage 1 or 2. Urine sediment examination was done with calculations of Perazella score (PS) and Chawla score (CS) at days 1, 3, and 7 and correlated with AKI progression and outcomes.Results Fifty-eight females and 22 males were enrolled in the study with a mean age of 61.10 ± 11.26 years, and initial serum creatinine at presentation was 2.06 ± 0.51 mg/dl.47.5% of patients progressed to stage 3 AKI, while 52.5% did not progress. Patients who progressed to stage 3 AKI had a significantly lower urine output at presentation, higher need for dialysis, higher mortality, higher serum creatinine, and lower eGFR at discharge and after 3 months. Both PS and CS at the time of diagnosis (day 1) showed no statistical difference between those with and without AKI progression. However, examination at day 3 and 7 revealed that AKI progressors had significantly higher PS and CS (p |
| Databáze: | Directory of Open Access Journals |
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