Anthracycline cardiomyopathy

Autor: Vasiliy Nefedovich Anokhin, Mikhail Ivanovich Chushkin, Aleksandr Viktorovich Kolganov, V N Anokhin, M I Chushkin, A V Kolganov
Jazyk: ruština
Rok vydání: 2011
Předmět:
Zdroj: Терапевтический архив, Vol 83, Iss 10, Pp 72-76 (2011)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
Popis: Anthracycline antibiotics are highly effective in the treatment of cancer, but their cardiotoxicity limits use of these antibiotics. A cardiotoxic action of anthracyclines provokes development of dilated cardiomyopathy with or without symptoms of cardiac insufficiency (CI). Anthracyclines have a long-term cardiotoxic action, therefore, with time, the rate of cardiomyopathy development increases. Follow-up echocardiography is an optimal method for assessment of cardiac function. Such parameters as left ventricular ejection fraction and the degree of the anteroposterior shortening are most essential. Cardiac failure symptoms are managed in the same way as in other pathology.
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