| Autor: |
Xi Chen, Ying-xue Li, Xun Cao, Meng-yun Qiang, Chi-xiong Liang, Liang-ru Ke, Zhuo-chen Cai, Ying-ying Huang, Ze-jiang Zhan, Jia-yu Zhou, Ying Deng, Lu-lu Zhang, Hao-yang Huang, Xiang Li, Jing Mei, Guo-tong Xie, Xiang Guo, Xing Lv |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-13 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1476-511X |
| DOI: |
10.1186/s12944-023-01830-2 |
| Popis: |
Abstract Background Dysregulation of lipid metabolism is closely associated with cancer progression. The study aimed to establish a prognostic model to predict distant metastasis-free survival (DMFS) in patients with nasopharyngeal carcinoma (NPC), based on lipidomics. Methods The plasma lipid profiles of 179 patients with locoregionally advanced NPC (LANPC) were measured and quantified using widely targeted quantitative lipidomics. Then, patients were randomly split into the training (125 patients, 69.8%) and validation (54 patients, 30.2%) sets. To identify distant metastasis-associated lipids, univariate Cox regression was applied to the training set (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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