Peripheral neuropathy associated with tofacitinib use in alopecia universalis

Autor:	Raghad Alharthi, Fatimah Alowirdi, Saba Alsuhaymi, Mohammed AlQahtani, Afaf Alsheikh
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	alopecia janus kinase-1 inhibitor janus kinase-3 inhibitor peripheral neuropathy tofacitinib Dermatology RL1-803
Zdroj:	Journal of Dermatology and Dermatologic Surgery, Vol 26, Iss 3, Pp 48-50 (2022)
Druh dokumentu:	article
ISSN:	2352-2410 2352-2429
DOI:	10.4103/jdds.jdds_69_19
Popis:	Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss. Alopecia universalis (AU) is the advanced form of AA characterized by complete scalp and body hair loss. Traditional medical therapies for AA include topical and intralesional corticosteroids, topical anthralin immunotherapy, and light therapy. Tofacitinib is a Janus kinase-1 and 3 inhibitor used in the treatment of AA. In this report, we describe a 20-year-old female with AU refractory to topical therapies; thus, she was started on tofacitinib. Mild peripheral neuropathy was an unanticipated side effect that could be kept into consideration.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/63ba23ca80cd461d86bae97908ba2e5c Zobrazit plný text záznamu View record in DOAJ