Retrograde reperfusion of renal grafts to reduce ischemic-reperfusion injury

Autor: Myltykbay Rysmakhanov, Aibolat Smagulov, Nadiar Mussin, Asset Kaliyev, Bazylbek Zhakiyev, Yerlan Sultangereyev, Gani Kuttymuratov
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Korean Journal of Transplantation, Vol 36, Iss 4, Pp 253-258 (2022)
Druh dokumentu: article
ISSN: 2671-8790
DOI: 10.4285/kjt.22.0053
Popis: Background : During transplantation, a kidney graft undergoes a cascade of pathological changes, referred to as ischemia-reperfusion injury (IRI), as it is incorporated into the bloodstream. Various studies have reported that retrograde reperfusion (RRP) leads to improved myocardial recovery and could reduce IRI in liver transplantation. This study investigated the effect of RRP in renal transplantation with a focus on reduction of kidney IRI. Methods : Between December 2019 and July 2022, 15 consecutive kidney transplants were performed with retrograde venous reperfusion. To conduct a comparative study and to recruit a control group, 15 kidney transplants that had been performed in the same center by the same two surgeons were retrospectively analyzed. Differences between the two groups were considered statistically significant at P0.05). The surgical technique for kidney transplantation was the same in both groups. On the first postoperative day, polyuria was less pronounced in the RRP group (P
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