| Autor: |
Sobhi M. Gomha, Thoraya A. Farghaly, Yahia Nasser Mabkhot, Mohie E. M. Zayed, Amany M. G. Mohamed |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Molecules, Vol 22, Iss 3, p 346 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/molecules22030346 |
| Popis: |
In this study, new derivatives of pyrazole, isoxazole, pyrazolylthiazole, and azolopyrimidine having a thiophene ring were synthesized under microwave irradiation. Their pharmacological activity toward bacteria and fungi inhibition was screened and compared to the references Chloramphenicol and Trimethoprim/sulphamethoxazole. The antimicrobial results of the investigated compounds revealed promising results and some derivatives have activities similar to the references used. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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