Patient–doctor relationship and adherence to capecitabine in outpatients of a German comprehensive cancer center

Autor: Hefner J, Berberich S, Lanvers E, Sanning M, Steimer AK, Kunzmann V
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Patient Preference and Adherence, Vol Volume 12, Pp 1875-1887 (2018)
Druh dokumentu: article
ISSN: 1177-889X
06284027
Popis: Jochen Hefner,1 Sara Berberich,2 Elena Lanvers,3 Maria Sanning,4 Ann-Kathrin Steimer,5 Volker Kunzmann6 1Section of Psychosomatic Medicine, Department of Internal Medicine II, University of Wuerzburg, Bavaria, Germany; 2Medical Student, Faculty of Medicine, University of Wuerzburg, Bavaria, Germany; 3Intensive Care Unit, Children’s Hospital of the City of Cologne, North Rhine-Westphalia, Germany; 4Department of Internal Medicine II, St Johannes Hospital Dortmund, North Rhine-Westphalia, Germany; 5Catholic Children’s Hospital Wilhelmsstift, Hamburg, Germany; 6Section of Clinical Oncology, Department of Internal Medicine II, University of Wuerzburg, Bavaria, Germany Purpose: The prescribing of oral chemotherapy agents has introduced the new challenge of ensuring patients’ adherence to therapy. Aspects of a close patient–doctor relationship are reported to be correlated with adherence to oral anticancer drugs, but data on capecitabine are scarce.Patients and methods: Sixty-four outpatients with a diagnosis of cancer and prescribed capecitabine were recruited from a German Comprehensive Cancer Center. We used the Patient–Doctor Relationship Questionnaire (PDRQ-9), the Medical Adherence Rating Scale (MARS), the Beliefs about Medicines Questionnaire (BMQ), and the Satisfaction with Information about Medicines Scale (SIMS) to assess patients’ perceptions and behavior. Medical data were extracted from the charts.Results: Non-adherence was reported by 20% of the 64 participants. The perceived quality of the patient–doctor relationship was high in general, but it did not emerge as a predictor of adherence in our survey (odds ratio [OR]=0.915, P=0.162, 95% CI=0.808–1.036). However, beliefs about medicine (OR=1.268, P
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