Foveal light and dark adaptation in patients with glaucoma and healthy subjects: A case-control study.

Autor: Ronald A J M Bierings, Marleen Kuiper, Casper M van Berkel, Tom Overkempe, Nomdo M Jansonius
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: PLoS ONE, Vol 13, Iss 3, p e0193663 (2018)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0193663
Popis: To determine whether foveal light and dark adaptation are affected in glaucoma.Case-control study with 23 glaucoma patients and 51 controls. Light and dark adaptation were measured twice. After 10 minutes pre-adaptation to 0.0032 cd/m2, the background luminance increased stepwise to 320 (5 log unit step) or 10,000 cd/m2 (6.5 log unit step) for 10 minutes, then it decreased back to 0.0032 cd/m2 for 30 minutes. Foveal contrast sensitivity [CS]) as a function of time was determined using a 1.15 degree increment. Time resolution of the experiments was 30 seconds. Multiple linear regression was used to analyse the effect of glaucoma on the CS plateau and adaptation time (time to reach the plateau minus 3 dB); analyses were adjusted for age and gender.After light adaptation to 320 and 10,000 cd/m2, glaucoma patients had a 0.22 (P
Databáze: Directory of Open Access Journals
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